Poietis NGB 6-axis robotic bioprinting arm holding a print plate
Make tissues real

Next generation
bioprinting

Single cells. Complex tissues. Laser-assisted bioprinting from the bench to the clinic.

7,000+Citations in laser-bioprinting research
100+Publications & patents
20+Years of R&D
2 µmLaser-print resolution

The science behind the platform: two decades of peer-reviewed laser-assisted bioprinting research, from foundational physics to clinical-grade manufacturing.

The machine and its accessories

One platform that grows with your science. The NGB-R® combines a laser source, a 6-axis robotic arm, and interchangeable heads and modules, each engineered for a step of the biofabrication workflow.

NGB-R® bioprinting system
NGB-R® system

A modular biofabrication platform

Upgrade and complete when you need. Multiple print heads, broad bio-ink compatibility, a fully automated workflow.

Engineered precision
2 µm

In-line microscope resolution

±0.02 mm

6-axis arm accuracy

1000 /sec

Laser droplet deposition

Laser printheadLaser
  • kHz, 1000 drops/sec, picoliter to nanoliter
  • Nozzle-free, no shear stress
  • Single cell to ~50 cells per droplet
In-line MicroscopeHRIM
  • 2 µm resolution, FOV 10 by 12 mm
  • Sterility-preserving quality control
  • ViewPrint targeted printing
6-Axis Robotic ArmROBOT
  • ±0.02 mm accuracy with speed control
  • Orchestrates all heads and modules
  • Broad compatibility of print supports
Microfluidic SystemMiFLU
  • 3 bioink reservoirs plus 1 cleaning
  • ±1 µL deposition
  • Automated multi-bioink workflow
PickCell ModulePICK
  • Spheroids & organoids 50 to 300 µm
  • AI detection, on-demand picking
  • Places aggregates into 3D constructs
Photocrosslinking HeadUVLP
  • 365 nm and 405 nm, dual wavelength
  • UV-crosslinkable bioinks (GelMA, PEGDA)
  • Pairs with pneumatic extrusion
Explore the full NGB-R® system

Explore it like the brochure

The same platform, laid out as the printed system overview. Select a point on the machine, or a subsystem, to highlight it.

NGB-R® laser-assisted bioprinter, front view

Two systems, one continuum

Built on the same architecture, the NGB-R® and NGB-C® ensure a seamless path from research to clinical translation.

NGB-R® for research
For research

NGB-R®

Explore a wide range of biofabrication strategies to improve the accuracy and reproducibility of your 3D culture models.

Discover NGB-R®
NGB-C® for GMP manufacturing
For GMP manufacturing

NGB-C®

The first clinical-grade, GMP-compliant bioprinter. A seamless continuum from research to clinical translation, ready for ATMP.

Discover NGB-C®

Four pillars

The platform is engineered around the four challenges of 3D bioprinting.

Pillar 1 Modularity & flexibility Upgrade and complete when you need. Multiple heads, broad bio-ink compatibility.
Pillar 2 Resolution & precision Laser-assisted bioprinting at single-cell precision, with in-line control.
Pillar 3 Robotization & automation A 6-axis arm and a fully automated workflow, driven by Zebr4D CAD.
Pillar 4 Biosafety & compliance Class II cabinet, sterilizable, end-to-end traceability. NGB-C® is GMP and ATMP ready.

Why laser. Nozzle-free, stress-free.

Laser-Assisted Bioprinting (LAB) is based on laser-induced forward transfer. A pulsed laser propels picoliter droplets from a donor slide to the receiver, with zero mechanical contact.

High-resolution laser bioprinting
No nozzle, no shear stress

Cells stay viable

No constricted channel means no shear damage. Cells are deposited intact, at high viability and high resolution.

Lower cost of use

Cheaper where it counts

Alternatives look cheaper to buy. At industrial scale, and for medical applications, laser precision lowers the real cost of use.

What you can achieve

Faithfully reproduce the 3D architecture and multicellular interactions that govern tissue function in vivo, across oncology, drug testing, and regenerative medicine.

Poieskin bioprinted skin substitute
Poieskin

The first therapeutic bioprinted tissue

Autologous full-thickness skin substitute, 40 cm², manufactured under GMP-compatible conditions. Phase I/IIa trial in progress at AP-HM, Marseille.

Building blocks

Stem cells, cells, organoids, hydrogels.

Targeted outcomes

3D models, organs-on-chips, tissue constructs.

Bioprinted liver tissue
Liver
Bioprinted neural and pancreas tissues
Neural
Markets Biopharma Drug screening Basic research Regenerative medicine Cosmetics
Research and proof

Proof, not claims

The platform is built on the published work of Poietis founder Fabien Guillemot and the laser-bioprinting field he helped establish at the University of Bordeaux. The underlying science is protected by a growing patent portfolio across Europe, the United States, China, Korea, and Japan.

7,026
Citations across the founding research record
34
h-index of the founding scientist
30+
Peer-reviewed publications on the technology
Guillotin, Guillemot et al.2010 · Biomaterials · 1,064 cites
Laser-assisted bioprinting of engineered tissue with high cell density and microscale organization.
Foundations
Keriquel et al.2017 · Scientific Reports · 542 cites
In situ printing of mesenchymal stromal cells for in vivo bone regeneration.
Bone
Abellán Lopez et al.2023 · Front. Bioeng. Biotech.
In vivo proof of concept of a large-size bioprinted dermo-epidermal substitute for permanent wound coverage.
Skin
Hall et al.2024 · Biofabrication
Laser-assisted bioprinting of targeted cartilaginous spheroids for high-density bottom-up tissue engineering.
Cartilage
View all publications

A research and clinical network

Poietis Biosystems collaborates with leading universities, research institutes, and hospitals across Europe and beyond.

KU Leuven TU Delft Leiden University UMC Utrecht University of Twente Maastricht University University of Barcelona

Clinical translation with AP-HM, Marseille. Scientific collaborations including MERLN Institute, Harvard, Northeastern, and Washington University.

The team

The people behind the platform

Poietis pioneered Laser-Assisted Bioprinting and has advanced high-resolution, cell-level deposition since 2014. Our engineers, biologists, and software builders turn that science - peer-reviewed and protected by 100+ patents across Europe, the United States, China, Korea, and Japan - into reliable NGB instruments, from the research bench to GMP manufacturing.

Fabien Guillemot
Fabien GuillemotFounder & CEO
Luc Milbergue
Luc MilberguePresident
Laurent Vrignaud
Laurent VrignaudGeneral manager
Antonio Iazzolino
Antonio IazzolinoDirector of R&D
SM
Soraya MezaibCommercial Director

Meet the team

More than a bioprinter

You are securing a bioprinting capability that can grow with you

Your projects. Your discoveries. Your regulatory ambition. Discover how the NGB platform accelerates biofabrication from your first prototype to clinical-grade manufacturing.